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运用聚合酶链反应（PCR）技术，检测输卵管妊娠组和对照组人乳头状瘤病毒（HPV）DNA，并在光镜下行病理学检查。发现输卵管妊娠组HPVDNA阳性率为7／25，其中输卵管局部阳性6／25，宫颈分泌物和外周血阳性均为1／25；病检输卵管炎占80％（20／25）。对照组输卵管HPVDNA均阴性，输卵管炎仅1例。两组间均有显著差异（P＜0．05）。输卵管妊娠组中HPVDNA阳性者，输卵管蜕膜炎为3／17，阴性者为1／18，二者亦有显著差异（P＜0．05）。提示HPV感染与输卵管妊娠的发生密切相关。
Polymerase chain reaction (PCR) was used to detect human papillomavirus (HPV) DNA in the tubal pregnancy group and the control group. Pathological examination was performed under light microscope. The positive rate of HPV DNA in tubal pregnancy was 7/25, of which 6/25 was positive in tubal, 1/25 in cervical secretions and peripheral blood, and 80% (20/25) of the patients were pathological salpingitis. Control group tubal HPVDNA were negative, salpingitis only 1 case. There was a significant difference between the two groups (P <0.05). Tubal pregnancy group HPVDNA positive, tubal decubitus was 3/17, the negative was 1/18, both were also significantly different (P <0.05). Tip HPV infection and tubal pregnancy are closely related.