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在山西省煤炭中心医院妇产科采集产前检查孕妇血清标本,采用酶联免疫吸附试验(ELISA)检测血清弓形虫IgG抗体。共调查466名孕妇,血清弓形虫IgG抗体阳性率为5.58%(26/466);不同年龄和职业孕妇弓形虫抗体阳性差异无统计学意义(χ2年龄=0.097,χ2职业=6.309,P>0.05);随文化程度的增高,弓形虫抗体阳性率逐渐降低(χ2=10.964,P<0.01);有动物接触史的孕妇弓形虫IgG抗体阳性率25.93%,无接触史的孕妇弓形虫IgG抗体阳性率为4.33%,差异有统计学意义(χ2=22.522,P<0.01);有不良孕产史的孕妇弓形虫IgG抗体阳性率为28.57%,无不良孕产史孕妇阳性率为4.11%,差异有统计学意义(Fisher’s Exact Test,P<0.01)。太原市孕妇弓形虫感染率较高,喂养宠物是弓形虫感染的重要因素。同时,弓形虫感染也是导致不良孕产结局的重要原因。应采取健康教育、早期检查及治疗等综合性预防控制弓形虫感染措施,提高生育质量。
Serum samples of prenatal pregnant women were collected at the Department of Obstetrics and Gynecology, Coal Center Hospital of Shanxi Province. Serum Toxoplasma gondii IgG antibody was detected by enzyme linked immunosorbent assay (ELISA). A total of 466 pregnant women were surveyed. The positive rate of IgG antibodies against Toxoplasma gondii was 5.58% (26/466). There was no significant difference in the antibody positive to Toxoplasma gondii between pregnant women of different ages and occupations (χ2 = age = 0.097, χ2 = 6.309, P> 0.05 ). The positive rate of Toxoplasma gondii antibody was gradually decreased with the increase of educational level (χ2 = 10.964, P <0.01). The positive rate of Toxoplasma gondii IgG antibody in pregnant women with contact history was 25.93% (Χ2 = 22.522, P <0.01). The positive rate of Toxoplasma gondii IgG antibody in pregnant women with history of adverse pregnancy was 28.57%, and the positive rate of pregnant women without history of adverse pregnancy was 4.11%, the difference was statistically significant (χ2 = 22.522, P <0.01) There was statistical significance (Fisher’s Exact Test, P <0.01). Toxoplasma infection in pregnant women in Taiyuan higher rate of feeding pets is an important factor in Toxoplasma infection. At the same time, Toxoplasma gondii infection is also an important cause of adverse pregnancy outcomes. Should take health education, early detection and treatment of comprehensive prevention and control of Toxoplasma gondii infection and improve reproductive quality.