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给正常人、萎缩性胃炎、胃溃疡、胃癌等10例患者皮下注射五肽胃泌素后,用胃管每15分钟收集一份样品,共收集64份样品,同时进行胃酸分泌量和cAMP分泌量的测定。观察结果:(1)在注射五肽胃泌素后,以一小时分泌量(指注射五肽胃泌素后胃酸和cAMP分泌量连续最多的4份样品之总和)计算,cAMP的分泌量是基础分泌量(注射前)的222.75％;胃酸分泌量为基础分泌量的426.03％。(2)以cAMP变量为X,胃酸变量为Y,统计了64份样品的二者之间的相关性,得相关系数γ=0.4772,故二者相关显著。为进一步探讨cAMP与胃酸变化的因果关系,设X为自变量,Y为因变量,求出回归系数b=0.0037,通过回归系数的显著性测验结果T_b=4.2,P<0.01,亦为非常显著意义。(3)注射五肽胃泌素后每15分钟的胃液样品作cAMP和胃酸分泌的时间反应曲线,可以看到二者分
To normal, atrophic gastritis, gastric ulcer, gastric cancer and other 10 patients injected pentagastrin subcutaneously after gastric tube every 15 minutes to collect a sample collected a total of 64 samples, while gastric acid secretion and cAMP secretion Determination of the amount. Observations: (1) After pentagastrin injection, the amount of cAMP secretion was calculated as the amount of secretion per hour (referring to the sum of gastric acid and cAMP secretion up to 4 consecutive samples after injection of pentagastrin) The basal secretion (before injection) of 222.75%; gastric acid secretion based on the amount of 426.03%. (2) The cAMP variable is X, the gastric acidity variable is Y, and the correlation between the 64 samples is statistically calculated, the correlation coefficient γ = 0.4772, so the correlation between the two is significant. To further explore the causal relationship between cAMP and gastric acid changes, set X as an independent variable, Y as a dependent variable, find the regression coefficient b = 0.0037, through the regression coefficient significance test results T_b = 4.2, P <0.01, is also very significant significance. (3) Time course of cAMP and gastric acid secretion in gastric juice sample after pentagastrin injection every 15 minutes, we can see the two points