肺泡巨噬细胞是肺脏重要的功能细胞。它不但可吞噬侵入肺脏的粒子,参与肺脏的防御和免疫;而且还能分泌大量的生物活性物质,维持肺脏和机体正常的生理活动。肺泡巨噬细胞与疾病的关系十分密切,矽肺中二氧化矽作用的重要靶细胞是肺泡巨噬细胞。谈及细胞的功能,必然联系到细胞的来源。肺泡巨噬细胞的来源,多年来,已进行了大量研究,现综述如下: 一、肺泡上皮来源:一些研究者认为肺泡内游离细胞的一部分是脱屑的肺泡上 Alveolar macrophages are important functional cells in the lungs. It can not only engulf the particles that invade the lungs, participate in the defense and immunity of the lungs, but also secrete a large amount of bioactive substances to maintain the normal physiological activities of the lungs and the body. Alveolar macrophages and the relationship between the disease is very close, the role of silicon dioxide in silicosis is an important target cell alveolar macrophages. Talking about the function of cells, must be linked to the source of cells. The source of alveolar macrophages, over the years, have conducted a large number of studies are summarized as follows: First, the alveolar epithelial origin: Some researchers believe that part of the alveolar free cells are scaling on the alveoli