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目的:研究自然流产发生原因及影响因素,为制定防治对策,指导优生优育及妇幼卫生保健提供依据。方法:采用病例对照研究方法,选择408例自然流产者作为病例组,同期选择正常妊娠分娩的产妇461名作对照组,调查可能的危险因素,并进行统计学分析。结果:单因素分析显示,年龄、职业、孕期阴道流血及保胎史、早孕家装史、妊娠期合并症、孕期服叶酸史、孕次、不良妊娠史是自然流产的影响因素(P<0.01)。多因素logistic回归分析显示,年龄、服装职业、化工职业、美容美发业、建筑装潢职业、孕期阴道流血、早孕家装史、早孕服叶酸、生殖道感染、病毒性感冒、其他内外科疾患、孕次、流产次数和不良妊娠史均是自然流产的独立影响因素。结论:高龄、服装职业、化工职业、美容美发职业、建筑装潢职业、孕期阴道流血、早孕家装史、孕期感染、孕次、流产次数和不良妊娠史均是自然流产的独立危险因素,孕期服叶酸是保护因素。
Objective: To study the causes and influencing factors of spontaneous abortion and provide basis for prevention and treatment measures, guidance of prenatal and postnatal care and maternal and child health care. Methods: A case-control study was conducted in which 408 cases of spontaneous abortion were selected as the case group. 461 mothers of the normal pregnancy were selected as the control group during the same period. The possible risk factors were investigated and statistically analyzed. Results: Univariate analysis showed that the factors influencing spontaneous abortion were age, occupation, history of vaginal bleeding and pregnancy history, history of early pregnancy, history of pregnancy, complications of pregnancy, folic acid in pregnancy, pregnancy history and adverse pregnancy history (P <0.01) . Multivariate logistic regression analysis showed that age, clothing occupations, chemical occupations, beauty salons, construction and decorating occupation, vaginal bleeding during pregnancy, history of early pregnancy decoration, early pregnancy folic acid, genital tract infections, viral influenza, other internal and external diseases, , The number of abortions and adverse pregnancy history are independent factors of spontaneous abortion. Conclusion: The elderly, clothing occupations, chemical occupations, beauty salons occupational, construction and decorating occupations, pregnancy vaginal bleeding, history of early pregnancy and home improvement, pregnancy infection, pregnancy times, abortion frequency and adverse pregnancy history are independent risk factors for spontaneous abortion. Is a protective factor