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目的探究重组人干扰素α-2b雾化吸入佐治小儿手足口病的临床效果。方法选取88例手足口病患儿作为研究对象,并将其随机分为对照组和观察组,每组44例。给予对照组常规治疗,观察组在常规治疗的基础上加用重组人干扰素α-2b。比较分析两组患者的治疗效果、皮疹消退时间、体温恢复时间和血红蛋白的变化情况。结果观察组的总有效率、皮疹消退时间、体温恢复时间均优于对照组,血红蛋白的下降幅度也低于对照组,且差异具有统计学意义(P<0.05)。结论重组人干扰素α-2b雾化吸入佐治小儿手足口病效果显著,值得临床推广应用。
Objective To investigate the clinical effect of recombinant human interferon α-2b aerosol inhalation on children with hand-foot-mouth disease. Methods Eighty-eight cases of hand-foot-mouth disease were selected as study subjects and randomly divided into control group and observation group, 44 cases in each group. The control group was given routine treatment. The observation group was given recombinant interferon alpha-2b on the basis of routine treatment. The curative effect, rash subsidence time, body temperature recovery time and hemoglobin changes were compared between the two groups. Results The total effective rate, rash subsidence time and body temperature recovery time in the observation group were better than those in the control group, and the decrease of hemoglobin in the observation group was also lower than that in the control group (P <0.05). Conclusion The effect of recombinant human interferon α-2b aerosol inhalation on children with hand-foot-mouth disease is significant and worthy of clinical application.