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目的:探究不同的梅毒检验方法检验梅毒螺旋体的检验效果准确性。方法:选取我院2015~2016年收治的患有梅毒的患者40例,采用螺旋体明胶颗粒凝集实验(TPPA)、酶联免疫吸附法(ELISA)和甲苯胺红不加热血清实验(TRUST)三种不同的方法对梅毒螺旋体进行检验,将三种检验方法的特异度、阳性率和敏感度进行对比。结果:采用三种检验方法检验处的阳性率均较高,TPPA的阳性率为100.00%,ELISA的阳性率为98.32%,TRUST的阳性率为89.37%,TPPA和ELISA检验处的阳性率明显高于TRUST,差异具有统计学意义(P<0.05),TPPA的敏感度为97.16%,ELISA的敏感度为84.17%,而TRUST只有70.49%,TPPA和ELISA的敏感度均明显高于TRUST,且TPPA和ELISA的特异度也均高于TRUST,差异具有统计学意义(P<0.05)。结论:对于临床上不同的梅毒情况,采用不同的检验方法,可以提高检验的准确性,避免误差。
Objective: To explore different syphilis test methods to check the accuracy of test results of Treponema pallidum. Methods: Forty patients with syphilis who were treated in our hospital from 2015 to 2016 were enrolled in this study. They were treated with spirochete gelatin particle agglutination test (TPPA), enzyme-linked immunosorbent assay (ELISA) and toluidine red unheated serum test (TRUST) Treponema pallidum with different methods to test, the specificity of the three test methods, the positive rate and sensitivity were compared. The positive rate of TPPA was 100.00%. The positive rate of ELISA was 98.32%. The positive rate of TRUST was 89.37%. The positive rates of TPPA and ELISA were significantly higher (P <0.05). The sensitivity of TPPA was 97.16%, the sensitivity of ELISA was 84.17%, while that of TRUST was only 70.49%. The sensitivity of TPPA and ELISA was significantly higher than that of TRUST, and the sensitivity of TPPA And specificity of ELISA were also higher than TRUST, the difference was statistically significant (P <0.05). Conclusion: For different clinically different syphilis cases, using different test methods can improve the accuracy of the test and avoid errors.