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目的应用MRI和1H-MRS评估针灸治疗对肥胖儿童腹部脂肪和肝内脂质含量的影响。方法 10例肥胖儿童(男7例,女3例)接受规律针灸治疗1个月,治疗前、后分别测量体质量、体质量指数(BMI)、腰围、臀围、腰臀比值(WHR)、腹部脂肪体积(应用MRI)及肝内脂质含量(应用1H-MRS)。结果针灸治疗后患者的BMI较治疗前减少3.50%(P=0.005)。腹腔内脂肪(VAT)体积、腹部总脂肪(TAT)体积及腹腔内脂肪/皮下脂肪比值(V/S)均较治疗前减少(P均<0.05)。体质量、腰围、臀围、WHR、腹部皮下脂肪(SAT)体积及肝内脂质含量(IHCL)均较治疗前减少,但差异无统计学意义(P>0.05)。针灸治疗前后腹部脂肪体积(SAT、VAT)与人体测量参数(体质量、BMI、腰围及臀围)显著相关,而肝内脂质含量(IHCL)与人体测量参数及腹部脂肪体积等指标之间均无相关性。结论针灸治疗可以显著减少肥胖儿童的BMI及腹部脂肪体积,特别是腹腔内脂肪体积。
Objective To evaluate the effects of acupuncture and moxibustion on abdominal fat and liver lipid content in obese children by MRI and 1H-MRS. Methods 10 obese children (7 males and 3 females) received regular acupuncture for 1 month. Before and after treatment, body mass, body mass index (BMI), waist circumference, hip circumference, WHR, Abdominal fat volume (using MRI) and intrahepatic lipid content (using 1H-MRS). Results The BMI of patients after acupuncture treatment was 3.50% lower than that before treatment (P = 0.005). The volume of intra-abdominal fat (VAT), the total abdominal fat (TAT) volume and intra-abdominal fat / subcutaneous fat ratio (V / S) decreased compared with before treatment (all P <0.05). Body mass, waist circumference, hip circumference, WHR, abdominal subcutaneous fat (SAT) volume and intrahepatic lipid content (IHCL) decreased compared with before treatment, but the difference was not statistically significant (P> 0.05). Abdominal fat volume (SAT, VAT) before and after acupuncture treatment was significantly correlated with anthropometric parameters (body mass, BMI, waist circumference and hip circumference), and between intrahepatic lipid content (IHCL) and anthropometric parameters and abdominal fat volume No correlation. Conclusion Acupuncture treatment can significantly reduce obese children’s BMI and abdominal fat volume, especially intra-abdominal fat volume.