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目的探讨SOD活性对尿毒症患者治疗观测的影响作用。方法用化学发光法测定SOD活性以比较血透前后SOD含量。结果健康对照组与慢性肾功能不全病人血浆SOD浓度分别为(285.31±68.41)u/mL与(196.53±45.42)u/mL(P<0.05),尿毒症病人血透前后血浆SOD浓度分别为(196.53±45.42)u/mL与(293.76±72.61)u/mL(P<0.05)。结论SOD活性是观察尿毒症患者疗效的有效指标,为临床治疗提供指导作用。
Objective To investigate the effect of SOD activity on the treatment of patients with uremia. Methods The activity of SOD was measured by chemiluminescence to compare the content of SOD before and after hemodialysis. Results The plasma levels of SOD in healthy control group and patients with chronic renal failure were 285.31 ± 68.41 u / mL and 196.53 ± 45.42 u / mL, respectively (P <0.05). The plasma SOD levels in patients with uremia before and after hemodialysis were ( 196.53 ± 45.42) u / mL and (293.76 ± 72.61) u / mL (P <0.05). Conclusion SOD activity is an effective indicator to observe the efficacy of uremia patients, and provide guidance for clinical treatment.