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目的:回顾性分析无创通气治疗SARS(传染性非典型肺炎)病ARDS(急性呼吸窘迫综合征)的作用 及其影响因素。方法:将2002年12月至2003年6月本院收治的21例出现ARDS的SARS患者,分为无创通气 组和有创通气组,并分析无创通气的作用及其成败的原因。结果:两组间的性别和年龄构成没有统计学的差 异;与有创通气组比较,无创通气组的医护人员/非医护人员的比率高(P<0.01)、有基础病/无基础病的比率 低(P<0.05)、呼吸频率低(P<0.05)和氧合指数(OI)高(P<0.01);其中氧合指数是无创治疗失败的弱危险 因素(OR=0.94,P<0.05),医护人员/非医护人员的比率是强危险因素(OR=57.79,P<0.05)。结论:无创 通气可用于治疗SARS继发的ARDS,指导患者正确配合无创通气可提高无创通气治疗成功率。
Objective: To retrospectively analyze the effect of noninvasive ventilation on acute respiratory distress syndrome (ARDS) and its influential factors in the treatment of SARS (infectious atypical pneumonia). Methods: 21 SARS patients with ARDS admitted to our hospital from December 2002 to June 2003 were divided into noninvasive ventilation group and invasive ventilation group. The effect of noninvasive ventilation and its causes were analyzed. Results: There was no significant difference in sex and age between the two groups. Compared with invasive ventilation group, the ratio of medical staff / non-medical staff in non-invasive ventilation group was higher (P <0.01), with underlying disease / no underlying disease The respiratory rate was lower (P <0.05) and the oxygenation index (OI) was higher (P <0.01). The oxygenation index was a weak risk factor of noninvasive treatment failure (OR = 0.94, P <0.05) ), And the ratio of medical staff / non-medical staff is a strong risk factor (OR = 57.79, P <0.05). Conclusion: Noninvasive ventilation can be used to treat ARDS secondary to SARS. Guiding patients with noninvasive ventilation can improve the success rate of noninvasive ventilation.