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目的观察辛伐他汀联合贝那普利对阵发性心房颤动(房颤)患者的治疗疗效。方法选择阵发性房颤58例,随机分成联合贝那普利组(22例,给予贝那普利+辛伐他汀治疗)、辛伐他汀组(18例,口服辛伐他汀治疗)和对照组(18例,仅给予常规治疗),随访1 a,观察心房颤动转复窦性心律后房颤复发率。结果联合贝那普利组患者心房颤动复发率明显少于对照组(P<0.05)。结论辛伐他汀联合贝那普利可减少阵发性房颤的复发。
Objective To observe the curative effect of simvastatin combined with benazepril in patients with paroxysmal atrial fibrillation (AF). Methods Fifty-eight patients with paroxysmal atrial fibrillation were randomly divided into benazepril group (n = 22, treated with benazepril and simvastatin), simvastatin (n = 18), and simvastatin Group (n = 18, treated only with routine treatment) were followed up for 1 year to observe the recurrence rate of atrial fibrillation after atrial fibrillation reversed sinus rhythm. Results The relapse rate of atrial fibrillation in the combined benazepril group was significantly less than that in the control group (P <0.05). Conclusion Simvastatin combined with benazepril can reduce the recurrence of paroxysmal atrial fibrillation.