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尘螨分布广泛,其蜕皮、尸体,尤其是代谢产物都是强烈致敏原,是引起各类过敏性疾病的重要病因之一,其中最主要的是引起过敏性哮喘。螨性过敏性疾病在全球的发生及其严重程度正日渐受到关注。免疫治疗作为一种针对螨性过敏性疾病的对因治疗,受到人们越来越多的重视。本文对螨性过敏性疾病免疫治疗方法,如特异性免疫治疗(SIT)、DNA-变应原免疫疗法、抗IgE单克隆抗体免疫疗法、抗CD11a单克隆抗体免疫疗法、趋化因子受体拮抗剂免疫疗法和抗FcγRⅠ单克隆抗体免疫疗法等进行了综述。
Dust mites are widely distributed, the molting, the body, especially the metabolites are highly allergen, is caused by one of the important causes of various allergic diseases, the most important of which is caused by allergic asthma. The occurrence and severity of mite allergic diseases in the world are receiving more and more attention. As a treatment for allergic diseases of mites, immunotherapy receives more and more attention. Immunotherapy of mite allergic diseases such as specific immunotherapy (SIT), DNA-allergen immunotherapy, anti-IgE monoclonal antibody immunotherapy, anti-CD11a monoclonal antibody immunotherapy, chemokine receptor antagonism Agent immunotherapy and anti-FcyRI monoclonal antibody immunotherapy were reviewed.