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目的观察法莫替丁联合泮托拉唑治疗消化性溃疡出血的临床效果。方法选取医院收治的消化性溃疡出血患者100例为研究对象,随机分为对照组和观察组,每组50例。2组患者均给予基础治疗,在此基础上,观察组给予静脉滴注泮托拉唑治疗,对照组给予静脉滴注法莫替丁治疗。治疗后观察2组患者的临床治疗效果与不良反应发生率。结果治疗后,观察组治疗总有效率为96.0%,高于对照组的76.0%(P<0.05);观察组不良反应发生率为4.0%,低于对照组的12.0%(P<0.05)。结论法莫替丁联合泮托拉唑静脉滴注治疗效果较好,不良反应少,安全性更高,值得临床推广应用。
Objective To observe the clinical efficacy of famotidine combined with pantoprazole in the treatment of peptic ulcer bleeding. Methods Selected 100 patients with peptic ulcer hemorrhage admitted to the hospital as the research object, were randomly divided into control group and observation group, 50 cases in each group. Two groups of patients were given basic treatment, on this basis, the observation group was given intravenous infusion of pantoprazole, the control group was given intravenous drip of famotidine. After treatment, the clinical efficacy and incidence of adverse reactions in the two groups were observed. Results After treatment, the total effective rate in the observation group was 96.0%, which was higher than that in the control group (76.0%, P <0.05). The adverse reaction rate in the observation group was 4.0%, which was lower than that in the control group (12.0%, P <0.05). Conclusion The combination of famotidine and pantoprazole intravenous drip is effective, with fewer adverse reactions and higher safety, which is worthy of clinical application.