抗体(免疫球蛋白)是免疫系统的重要组成部分,长久以来由于它的特异性和高亲和力被应用于分离和纯化靶抗原。近年研究指出,抗体还能在细胞内结合其相应抗原,在细胞内以特殊的方式干扰重要的生物过程。因此,细胞内抗体在理论上可能是针对病毒感染和肿瘤疾病的特异性治疗方法。 Antibodies (immunoglobulins) are an important part of the immune system and have long been used for the isolation and purification of target antigens due to their specificity and high affinity. Recent studies indicate that antibodies can also bind their respective antigens within the cell and interfere with important biological processes in a particular manner within the cell. Therefore, the intracellular antibody may theoretically be a specific treatment for viral infections and oncological diseases.