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目的:探讨影响输卵管妊娠保守治疗血绒毛膜促性腺激素(HCG)下降速度和幅度的相关因素。方法:回顾分析输卵管妊娠保守治疗患者93例,其中药物治疗30例(A组),保守手术治疗30例(B组),保守手术加药物治疗33例(C组),取30例行输卵管妊娠患侧切除术患者为对照组(D组);4组治疗后定期检测血HCG。结果:保守手术加药物治疗患者血HCG下降至正常的时间,明显短于单纯药物治疗组和手术治疗组(P<0.01);术前血HCG高者治疗后下降至正常所需时间长。结论:输卵管保守手术治疗血HCG下降明显快于药物治疗,保守手术加口服米非司酮治疗可加快术后血HCG下降的速度和幅度。
Objective: To explore the factors influencing the rate and magnitude of conservative reduction of blood chorionic gonadotropin (HCG) in tubal pregnancy. Methods: A total of 93 conservative treatment of tubal pregnancy were retrospectively analyzed. Among them, 30 cases were treated with drug (group A), 30 cases were treated conservatively (group B), 33 cases were treated conservatively with drugs (group C) The patients with ipsilateral resection were control group (group D). Blood HCG was detected regularly in 4 groups after treatment. Results: The blood HCG decreased to normal in patients with conservative surgery and drug treatment, which was significantly shorter than that in the simple drug-treated group and the surgical treatment group (P <0.01). The preoperative serum HCG levels decreased to normal after long-term treatment. Conclusion: The conservative treatment of tubal blood HCG decreased significantly faster than drug treatment, conservative surgery and oral mifepristone can speed up the rate of decline of blood HCG after surgery.