目的了解2012年北京市西城(北)区托幼机构及学校手足口病疫情流行特征,为预防手足口病聚集提供依据。方法对2012年北京市西城(北)区托幼机构和学校内发生的手足口病疫情报告、规模、分布特点、患者临床表现、实验室检测等特征进行分析。结果 2012年北京市西城(北)区托幼机构及学校共报告手足口病聚集性疫情35起,波及14 038人,共报告病例105例,平均罹患率0.75%;其中1人为重症病例,无死亡病例。疫情来源以校医或园医报告为主,疫情持续时间中位数为12 d(10~21 d);疫情报告时间以5—7月为主,占报告总数的80.00%。35起疫情中,实验室检测阳性21起。结论托幼机构及学校是手足口病疫情高发场所,早期发现手足口病疫情是防止手足口病局部暴发的重要措施。 Objective To understand the prevalence of HFMD in kindergartens and schools in Xicheng (North) District of Beijing in 2012 and provide basis for prevention of hand-foot-mouth disease aggregation. Methods The characteristics of hand, foot and mouth disease (HFMD) epidemic, scale, distribution, clinical manifestations and laboratory tests of nurseries and schools in Xicheng (North) district of Beijing in 2012 were analyzed. Results In 2012, the kindergartens and schools in Xicheng (North) district of Beijing reported a total of 35 aggregated outbreaks of hand-foot-mouth disease, affecting 14 038 people. A total of 105 cases were reported, with an average attack rate of 0.75%. Among them, 1 was severe and none Deaths. The source of the outbreak was mainly school physician or doctor’s report. The median duration of the outbreak was 12 days (10-21 days). The epidemic reporting time was mainly in May-July, accounting for 80.00% of the total. Of the 35 outbreaks, 21 were positive in laboratory tests. Conclusion Nurseries and schools are the high incidence of hand-foot-mouth disease. The early detection of hand-foot-mouth disease is an important measure to prevent the outbreak of hand-foot-mouth disease.