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目的评价2011年—2014年成都市21家医院铂类药物的使用情况。方法调取成都市21家医院2011年—2014年铂类药物的相关用药信息,统计分析药物剂型、使用金额、用药频度(frequency of drug use,DDDs)、日均费用(defined daily cost,DDC)及药品排序比[药品使用金额排序(B)与各药DDDs排序(A)的比值,B/A]。结果 2011年—2014年铂类药物的总使用金额和DDDs逐年增长,奥沙利铂使用金额最高,卡铂的使用金额逐年递增。从排序来看,奥沙利铂、奈达铂、洛铂连续4年排名均为第1、2、5位;2011年—2014年铂类药物总DDDs呈上升趋势,顺铂的DDDs排名持续居于首位,奥沙利铂其次;铂类药物的DDC及排序相对稳定,卡铂和洛铂的B/A值接近于1.00。结论成都市医院铂类药物使用符合安全有效、方便经济的原则。
Objective To evaluate the use of platinum drugs in 21 hospitals in Chengdu from 2011 to 2014. Methods The related medication information of platinum drugs in 21 hospitals in Chengdu from 2011 to 2014 were collected and statistically analyzed for drug dosage form, usage amount, frequency of drug use (DDDs), defined daily cost (DDC ) And drug rankings [ratio of drug use amount (B) to drug DDDs rankings (A), B / A]. Results From 2011 to 2014, the total amount of platinum drugs used and the DDDs increased year by year. The amount of oxaliplatin used was the highest. The amount of carboplatin used increased year by year. In terms of the rankings, oxaliplatin, nedaplatin, and lobaplatin ranked No. 1, 2 and 5 for 4 consecutive years respectively. From 2011 to 2014, the total DDDs of platinum drugs showed an upward trend and the rankings of DDDs of cisplatin continued Living in the first place, followed by oxaliplatin; DDC and ranking of platinum drugs is relatively stable, B / A values of carboplatin and lobaplatin close to 1.00. Conclusion The use of platinum drugs in Chengdu Hospital is in line with the principle of safety and effectiveness and convenience.