论文部分内容阅读
背景:吸毒人群中乙型肝炎病毒(hepatitisBvirus,HBV)感染率高与该人群性行为特点有关,吸毒人群中HBV、丙型肝炎病毒(hepatitisCvirus,HCV)重叠感染率与其性行为特点的关系如何?目的:了解吸毒人群性行为特点与HBV,HCV重叠感染的关系。设计:2001-01-01/31进行的横断面调查。单位:一所市级医院检验科,一所大学的公共卫生学院流行病学教研室,一所专业戒毒所。对象:在长沙新开铺戒毒所、株洲白马垅女子戒毒所中随机选取452例男性吸毒者和320例女性吸毒者做为研究对象。方法:用自编问卷调查吸毒者的性行为特点,并用ELISA法测定其血清中HBV表面抗原和HCV抗体。主要观察指标:吸毒者HBV和HCV重叠感染与性行为、性伙伴的个数、是否使用安全套的关系。结果:吸毒者HBV,HCV总的重叠感染率为21.2%;男性、女性重叠感染率分别为29.6%和9.4%,差异有显著性(χ2=46.016,P<0.01)。有无性行为的男性、女性吸毒者之间HBV,HCV重叠感染率差异无显著性(χ2=3.775,P>0.05);随着性伙伴个数的增加,HBV,HCV重叠感染率大体呈上升的趋势,差异有显著性(χ2=9.846,P<0.05);男性安全套使用率低于女性,差异有显著性(U=14.80,P<0.01)。结论:男性、女性吸毒者HBV和HCV的重叠感染率与是否有性行为无关,男性重叠感染高于女性,男、女性重叠感染率
BACKGROUND: The high infection rate of hepatitis B virus (HBV) among drug users is related to the sexual behavior of the population. What is the relationship between the overlapping infection rates of hepatitis C and hepatitis C virus (HCV) and their sexual behavior in drug users? Objective: To understand the relationship between sexual behavior characteristics of HBV drug users and overlap infection of HBV and HCV. Design: Cross-sectional survey conducted on January 01, 2001. Unit: a municipal hospital laboratory, a university public health college epidemiology department, a professional detoxification center. PARTICIPANTS: 452 male drug addicts and 320 female drug addicts were randomly selected from the newly opened drug rehabilitation center in Changsha and Zhuma Baima Zhuo women drug addiction treatment center. Methods: The self-made questionnaires were used to investigate the sexual behavior of drug addicts, and the serum HBV antigens and anti-HCV antibodies were measured by ELISA. MAIN OUTCOME MEASURES: Duplication of HBV and HCV among HIV-infected drug users and the number of sex partners and condom use. Results: The total overlap rate of HBV and HCV among drug users was 21.2%. The overlap rates of male and female were 29.6% and 9.4%, respectively. There was significant difference (χ2 = 46.016, P <0.01). There was no significant difference in the prevalence of HBV and HCV infection between male and female drug users (χ2 = 3.775, P> 0.05). With the increase of the number of sexual partners, the prevalence of HBV and HCV overlap was generally increased (Χ2 = 9.846, P <0.05). The rate of condom use in males was lower than that in females with a significant difference (U = 14.80, P <0.01). Conclusion: The overlapping infection rates of HBV and HCV in male and female drug users are not related to the presence or absence of sexual behavior. The overlap rate of male and female overlap is higher than that of female, and the overlapping infection rate of male and female