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目的:回顾分析肾移植后白内障患者的临床资料,探讨其成因和防治方法。方法:收集1986年10月~2007年12月526例肾移植术后并发白内障患者5例(10只眼)的临床资料,分别对免疫抑制药用药情况和白内障手术结果进行分析。结果:本组病例需要手术治疗的肾移植后白内障的发生率为0.95%;高低剂量糖皮质激素组的白内障发生率分别为1.97%和0.31%。5例9只眼行白内障摘除及人工晶体植入术,手术后视力恢复正常水平。结论:低剂量糖皮质激素可降低肾移植后白内障的发生率,白内障摘除联合人工晶体植入手术是治疗白内障的可靠方法。
OBJECTIVE: To retrospectively analyze the clinical data of patients with cataract after renal transplantation and discuss the causes and prevention methods. Methods: Clinical data of 526 cases of cataract patients after renal transplantation (10 eyes) from October 1986 to December 2007 were collected. The immunosuppressive drugs and the results of cataract surgery were analyzed respectively. Results: The incidence of cataract after renal transplantation in this group of patients was 0.95%. The incidence of cataract in high and low glucocorticoid group was 1.97% and 0.31%, respectively. Five patients (9 eyes) underwent cataract extraction and intraocular lens implantation. The visual acuity returned to normal after operation. Conclusions: Low dose glucocorticoids can reduce the incidence of cataract after renal transplantation. Cataract extraction combined with intraocular lens implantation is a reliable method for the treatment of cataract.