论文部分内容阅读
目的探讨阿卡波糖联合胰岛素治疗2型糖尿病的临床疗效观察。方法选择我院2008年10月至2009年10月2型糖尿病患者102例,随机将上述患者分为两组,观察组和对照组。其中观察组52例,对照组50例。两组患者均给予糖尿病饮食,糖尿病健康教育等。观察组患者三餐时嚼服阿卡波糖25～100mg,晚上22点注射甘精胰岛素,其实剂量为0.2U/(kg·d);对照组患者早餐、晚餐前半个小时注射诺和灵30R,起始剂量为0.4U/(kg·d)在治疗过程中定时观察两组患者血糖情况。结果两组患者血糖达标时间比较,差异无统计学意义,P>0.05;两组患者胰岛素每天用量比较,差异有统计学意义,P<0.05;两组患者低血糖发生率比较,差异有统计学意义,P<0.05。结论阿卡波糖联合甘精胰岛素治疗2型糖尿病低血糖发生率低,且可减少胰岛素的用量,临床效果显著,值得借鉴。
Objective To investigate the clinical efficacy of acarbose combined with insulin in the treatment of type 2 diabetes mellitus. Methods A total of 102 patients with type 2 diabetes mellitus from October 2008 to October 2009 in our hospital were randomly divided into two groups: observation group and control group. 52 cases in the observation group and 50 cases in the control group. Two groups of patients were given diabetes diet, diabetes health education. Patients in the observation group chewed Acarbose 25 to 100 mg at three meals a day and glargine at 22:00 a.m. in a dose of 0.2 U / (kg · d). Patients in the control group received Novolin 30R for breakfast and half an hour before dinner , The initial dose of 0.4U / (kg · d) in the treatment of regular observation of two groups of patients with blood glucose. Results The two groups of patients with blood glucose compliance time, the difference was not statistically significant, P> 0.05; two groups of patients daily insulin dosage, the difference was statistically significant, P lt; 0.05; two groups of patients with hypoglycemia compared with the difference was statistically significant Significance, P <0.05. Conclusion Acarbose combined with insulin glargine treatment of type 2 diabetes low incidence of hypoglycemia, and can reduce the amount of insulin, the clinical effect is significant, it is worth learning from.