急性心肌梗塞患者致死的主要原因有二,即原发性心律失常和喷血功能衰竭(泵出衰竭)。由于监护技术的应用及更为积极的治疗和预防,死于心律失常者已见减少,但因表现为心源性休克或/及肺水肿的心肌衰竭而致死者仍相当多。在由于泵出衰竭而致死的患者,存活并能收缩的心肌数量比由其他原因如心律失常而死亡者为少。因此,在冠状动脉闭塞后,任何能减少心肌坏死范围并从而减少喷血功能衰竭的治疗方法是极其有用的,它不仅能降低即时死亡率,更重要的是能使生存的冠状动脉闭塞患者保留更多的存活心肌。这些患者较少发生慢性心力衰竭,保存有较多的心肌储备。心肌梗塞的发生和范围是由于氧的供求不平衡所致。当冠状动脉发生闭塞后,心肌 Two main causes of death in patients with acute myocardial infarction, namely, primary arrhythmia and spurt failure (pump failure). Due to the application of monitoring techniques and the more aggressive treatment and prevention, fewer have died of arrhythmia, but those who are still deceased due to heart failure characterized by cardiogenic shock and / or pulmonary edema are still quite numerous. In patients who die as a result of pump failure, the number of surviving and contracting myocardium is less than those who die from other causes, such as arrhythmias. Therefore, any treatment that reduces the extent of myocardial necrosis and thereby reduces splenic blood flow after coronary artery occlusion is extremely useful, not only to reduce immediate mortality but, more importantly, to preserve survival in patients with coronary artery occlusions More surviving myocardium. These patients less chronic heart failure, save more myocardial reserve. The incidence and extent of myocardial infarction is due to the imbalance between supply and demand of oxygen. When the coronary artery occlusion, myocardial