早泄是最常见的男性性功能障碍,其在全球的发病率约为30%~40%~([1])。选择性5-羟色胺再摄取抑制剂(SSRI)是一类抗抑郁药物,因发现其在治疗抑郁症的过程中出现射精延迟、性高潮延迟的副作用,而被用来治疗早泄~([2])。盐酸舍曲林是一种新型的SSRI类药物,其药代动力学吸收快、安全性较高、副作用较少。国内外的研究均表明其对早泄的治疗具有一 Premature ejaculation is the most common male sexual dysfunction, and its incidence in the world is about 30% ~ 40% ~ ([1]). Selective serotonin reuptake inhibitors (SSRIs) are a class of antidepressant drugs that have been used to treat premature ejaculation due to delayed ejaculation or delayed orgasm in the treatment of depression (2) ). Sertraline hydrochloride is a new class of SSRIs with fast pharmacokinetics, high safety and fewer side effects. Domestic and foreign studies have shown that the treatment of premature ejaculation has one