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研究微波固化保肢术提高患者生存率的免疫学机制。方法：应用色散比浊法检测患者血清Ｃ３、Ｃ４含量，应用红细胞Ｃ３ｂ受体花环（Ｃ３ｂＲＲ）、免疫复合物花环（ＣＩＣＲＲ）及直接肿瘤花环（ＴＲＲ）检测红细胞免疫功能。结果：２０例微波固化保肢组患者及２０例截肢组患者术前Ｃ３ｂＲＲ、ＴＲＲ降低，ＣＩＣＲＲ升高（Ｐ＜０．０５），Ｃ３、Ｃ４变化不明显；术后１４天时，微波组较截肢组Ｃ３ｂＲＲ、ＴＲＲ升高（Ｐ＜０．０５），ＣＩＣＲＲ变化不明显，２８天时两组各项指标恢复正常（Ｐ＜０．０５）。结论：微波固化保肢术可提高患者的红细胞免疫功能。
To study the immunological mechanism of microwave-assisted limb salvage for improving patient survival. Methods: The levels of C3 and C4 in serum of patients were detected by dispersive turbidimetry. Erythrocyte immune function was detected by C3b receptor garland (C3bRR), CICRR and TRR. RESULTS: The preoperative C3bRR and TRR were decreased and the CICRR was increased (P<0.05) in 20 patients in the microwave-cure limb-sparing group and 20 patients in the amputee group. C3 and C4 did not change significantly. In the 14-day postoperative period, the microwave group was more amputated. The group C3bRR and TRR were elevated (P<0.05), and the CICRR did not change significantly. On the 28th day, the indexes of the two groups returned to normal (P<0.05). CONCLUSIONS: Microwave solidified limb salvage can improve patients’ red blood cell immune function.