论文部分内容阅读
研究者检查了患非贲门胃癌患者一级近亲中胃萎缩和低胃酸的患病率及这些癌前异常和Hp感染的相关性,还检查了经根除Hp感染后这些异常的可逆性。 方法:在40例胃癌患者的100例一级近亲中,诊断胃癌时的平均年龄为67岁(37～88岁),100例癌症患者近亲的平均年龄为43.7岁(20～67岁);另有100例没有胃癌家庭史的健康受试者作为对照组,进行胃酸分泌研究。所有受试者都进行了~(14)C-尿素呼气试验,胃癌患者近亲和健康对照组进行了酸分泌研究。癌症患者近亲和非溃疡消化不良的对照组进行了上消化道内镜检查并获得了胃粘膜活检标本,均检查了血清抗Hp IgG抗体。
The researchers examined the prevalence of gastric atrophy and hypogastric acid in first-degree relatives of patients with non-cardia gastric cancer and the association of these precancerous and Hp infections and examined the reversibility of these abnormalities after eradication of Hp infection. Methods: The average age of 100 first-degree relatives in 40 cases of gastric cancer was 67 years (37-88 years) when diagnosing gastric cancer. The average age of 100 relatives of cancer patients was 43.7 years (20-67 years) There are 100 healthy subjects without a family history of gastric cancer as a control group for gastric acid secretion studies. All subjects underwent ~ (14) C-urea breath test, and gastric acid secretion was studied in close relatives of gastric cancer patients and healthy controls. The close relatives of cancer patients and non-ulcer dyspepsia control group were subjected to upper gastrointestinal endoscopy and gastric mucosal biopsy specimens were obtained, and serum anti-Hp IgG antibodies were examined.