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目的分析妊娠合并隐性梅毒治疗与围生儿的预后关系。方法 104例妊娠合并隐性梅毒患者,依据妊娠期有无接受全疗程抗梅毒治疗分为A组(38例,妊娠<20周,早期治疗组)、B组(35例,妊娠20~37周,晚期治疗组)、C组(31例,妊娠>39周治疗组)。对三组围生儿不良预后进行观察比较。结果 A组正常新生儿率92.1%(35/38),围生儿不良预后率7.9%(3/38);B组正常新生儿率85.7%(30/35),围生儿不良预后率14.3%(5/35);C组正常新生儿率64.5%(20/31),围生儿不良预后率35.5%(11/31)。C组正常新生儿率显著低于A组、B组,其围生儿不良预后率显著高于A组、B组,差异具有统计学意义(P<0.05)。结论妊娠合并隐性梅毒治疗对改善围生儿不良结局和预后具有重要意义,值得在临床中大力推广应用。
Objective To analyze the relationship between the treatment of latent syphilis in pregnancy and the prognosis of perinatal children. Methods A total of 104 pregnant women with latent syphilis were divided into group A (38 cases, pregnancy <20 weeks, early treatment group), group B (35 cases, pregnancy 20 ~ 37 weeks , Late treatment group), C group (31 cases, pregnancy> 39 weeks treatment group). The adverse prognosis of three groups of infants were observed and compared. Results The normal newborn rate was 92.1% (35/38) in group A and 7.9% (3/38) in normal children. The normal newborn rate in group B was 85.7% (30/35) % (5/35). The normal newborn rate in group C was 64.5% (20/31), and the rate of poor prognosis in perinatal children was 35.5% (11/31). The normal newborn rate in group C was significantly lower than that in group A and group B. The poor prognosis rate in perinatal group was significantly higher than that in group A and group B (P <0.05). Conclusion The treatment of pregnancy complicated with latent syphilis is of great significance in improving the outcome and prognosis of perinatal children and it is worth to be popularized in clinical practice.