脑损伤是新生儿时期危害严重的疾病之一。随着新生儿急救水平的发展,脑损伤新生儿存活率显著提高,但脑损伤引发的后遗症问题更为普遍,并引起了广大儿科专家的关注。因为围生期大脑处于发育阶段,科学研究难度大,以至于发病机制并不十分清楚,所以,新生儿脑损伤的临床治疗较困难。现就新生儿脑损伤的病因、病理改变、发病机制、临床表现、损伤后修复机制、防治和预后进行分析。 Brain damage is one of the most devastating diseases in the neonatal period. With the development of neonatal first aid, the survival rate of newborns with brain injury is significantly increased, but the sequelae problems caused by brain injury are more common and have aroused the attention of the majority of pediatricians. Because the perinatal brain in developmental stage, scientific research is so difficult that the pathogenesis is not very clear, so the clinical treatment of neonatal brain injury more difficult. Neonatal brain injury are now on the etiology, pathological changes, pathogenesis, clinical manifestations, post-injury repair mechanism, prevention and prognosis analysis.