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目的探讨Ｂｅｌ麻痹与疱疹类病毒及柯萨奇Ｂ组病毒感染的关系。方法采用间接ＥＬＩＳＡ法检测Ｂｅｌ麻痹患者血清中水痘带状疱疹病毒（ＶＺＶ）和单纯疱疹病毒Ⅰ型、Ⅱ型（ＨＳＶ１，２）及柯萨奇Ｂ组病毒１～６型（ＣＢ１～６）特异性ＩｇＭ、ＩｇＧ抗体的阳性率。结果患者组血清抗体阳性率与对照组相比：ＶＺＶＩｇＭ、ＩｇＧ阳性率差异有显著性（Ｐ＜００１，Ｐ＜００５），ＨＳＶ１ＩｇＭ、ＩｇＧ阳性率差异有显著（Ｐ＜００５，Ｐ＜００１），ＨＳＶ２ＩｇＭ阳性率差异有显著性（Ｐ＜００５），但ＨＳＶ２ＩｇＧ阳性率差异无显著性（Ｐ＞００５），在ＣＢ１～６ＩｇＭ、ＩｇＧ阳性率检测中，除ＣＢ５ＩｇＭ差异有显著性（Ｐ＜００５）外，其余型别两组差异均无显著性（Ｐ＞００５）。结论Ｂｅｌ麻痹与ＶＺＶ、ＨＳＶ１感染有一定关系。
Objective To investigate the relationship between Bel paralysis and herpes virus and coxsackie B virus infection. Methods Serum varicella zoster virus (VZV) and herpes simplex virus type 1 and type 2 (HSV1,2) and Coxsackie B virus type 1 to 6 (CB1 ~ 6) were detected by indirect ELISA in patients with Bel paralysis Sex IgM, IgG antibody positive rate. Results The positive rate of serum antibody in patients was significantly higher than that of the control group (P <001, P <005), and the positive rate of HSV1IgM and IgG was significant (P <005, P <001), the positive rate of HSV2IgM was significantly different (P <005), but the positive rate of HSV2IgG was no significant difference (P> 005) 6 IgM, IgG positive rate detection, except for CB5 IgM difference was significant (P <0 05), the remaining type of two groups showed no significant difference (P> 0 05). Conclusion Bel paralysis and VZV, HSV1 infection have a certain relationship.