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目的探索治疗老年煤工尘肺及其结核合并2型糖尿病(T2DM)患者口服降糖药物失效的有效方法。方法对煤工尘肺及其结核患者采用对症处理和全程督导化疗方案(DOTS)的同时,停用口服药物,予诺和灵30R胰岛素每日2次早晚餐前30min皮下注射。结果经诺和灵30R胰岛素治疗后空腹血糖(FBG)、餐后2h血糖(2hBG)、糖化血红蛋白(HbA1C)明显下降(P<0.01),总胆固醇(TC)、三酰甘油(TG)较治疗前也有明显下降(P<0.05)。结论诺和灵30R胰岛素治疗老年煤工尘肺及其结核合并T2DM患者口服降糖药物失效的患者的疗效确切,使用方便,不良反应少,值得推广。
Objective To explore an effective method for the treatment of elderly coal workers pneumoconiosis and tuberculosis patients with type 2 diabetes (T2DM) oral hypoglycemic drugs failure. Methods During the symptomatic treatment and full-course chemotherapy (DOTS), coal workers’ pneumoconiosis and their tuberculosis patients were stopped taking oral medication. The patients were injected subcutaneously with prenatal and prenuptial doses of 30R insulin for 3 hours a day. Results After fasting blood glucose (FBG), 2hBG and HbA1C decreased significantly (P <0.01), total cholesterol Before the significant decline (P <0.05). CONCLUSION Novolin 30R insulin is effective and effective in the treatment of elderly coal worker pneumoconiosis and tuberculosis patients with T2DM due to oral hypoglycemic drugs. It is easy to use and has few adverse reactions and is worth promoting.