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皮肤上皮性肿瘤种类繁多,在临床皮肤肿瘤病理检查工作常常需要借助各种免疫标志物的检测,但由于皮肤上皮性肿瘤的复杂性和各个肿瘤免疫标记表达的重叠,其对诊断和鉴别诊断的帮助仍然有限。探讨更多新标志物对皮肤上皮性肿瘤的诊断价值,依然是重要的任务。近年毛囊干细胞标记物CK15和Nestin被用于皮肤附属器肿瘤的病理诊断和皮肤附属器肿瘤与皮肤转移性癌的鉴别,是一种新的诊断思路。
Epidermal tumors of the skin are numerous and often require the detection of various immune markers in the pathological examination of clinical skin tumors. However, due to the complexity of the skin epithelial tumors and the overlap of the expression of various tumor immunological markers, their diagnostic and differential diagnosis Help is still limited. It is still an important task to explore the diagnostic value of more new markers on skin epithelial tumors. In recent years, hair follicle stem cell markers CK15 and Nestin were used in the pathological diagnosis of skin adnexal tumors and skin adnexal tumors and skin metastatic cancer, is a new diagnostic idea.