论文部分内容阅读
目的:观察贝尼地平治疗老年原发性高血压患者的疗效及其对左室舒张功能影响。方法:原发性高血压70例,年龄60~81岁。随机分为2组,A组36例,应用贝尼地平片;B组34例,口服复方降压片。2组均连续用药8周,用多普勒超声心动图进行左室舒张功能观察。结果:降压疗效总有效率A组为86.1%,B组为82.4%。2组比较差异无统计学意义(P>0.05)。左室舒张功能各指标在A组用药前后比较差异有统计学意义(P<0.01),B组亦差异有统计学意义(P<0.05)。A组左室舒张功能各指标改善程度优于B组(P<0.05),治疗期间未见严重不良反应。结论:贝尼地平对老年高血压疗效好,安全,且有改善左室舒张功能的作用。
Objective: To observe the efficacy of benidipine in the treatment of elderly patients with essential hypertension and its effect on left ventricular diastolic function. Methods: 70 cases of essential hypertension, aged 60 to 81 years old. Randomly divided into two groups, A group of 36 cases, the use of benidipine tablets; B group 34 cases, oral compound antihypertensive tablets. The two groups were continuous medication for 8 weeks, with left ventricular diastolic function observed by Doppler echocardiography. Results: The total effective rate of antihypertensive efficacy was 86.1% in group A and 82.4% in group B. There was no significant difference between the two groups (P> 0.05). The indexes of left ventricular diastolic function were significantly different in group A before and after treatment (P <0.01), but also in group B (P <0.05). A group of left ventricular diastolic function index improved better than the B group (P <0.05), no serious adverse reactions during treatment. Conclusion: Benidipine is effective and safe for elderly patients with hypertension and has the effect of improving left ventricular diastolic function.