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使用放射免疫分析方法和微穿孔技术,观察了切断大鼠腹部迷走神经腹干和刺激其向中端对杏仁核、下丘脑和胃的生长抑素含量的影响。切断迷走神经,杏仁核生长抑素含量无明显改变,外侧视前区、下丘脑腹内侧核和室旁核的生长抑素含量下降,胃窦与胃体的粘膜和肌层的生长抑素含量也下降,表明腹部迷走神经冲动对下丘脑和胃的生长抑素有紧张性影响。刺激腹部迷走神经向中端,杏仁的内侧核、外侧核和中央核的生长抑素含量减少,外侧视前区、下丘脑腹内侧核和室旁核的生长抑素含量增加,胃窦部粘膜和肌层的生长抑素含量也增加,提示了杏仁核和下丘脑一些核团的生长抑素可能在内脏传入信息的中枢整合活动中起作用。
Radioimmunoassay and micro-perforation techniques were used to observe the effects of cutting off the ventral vagus nerve of the abdomen and stimulating the somatostatin content of the amygdala, hypothalamus and stomach to the midpoint. Severance of the vagus nerve resulted in no significant change in the content of somatostatin in the amygdala. The content of somatostatin decreased in the preoptic area, the ventromedial hypothalamus and the paraventricular nucleus, and the somatostatin content in the gastric mucosa and muscular layer decreased , Indicating that vagal impulses in the abdomen have a tense effect on somatostatin in the hypothalamus and stomach. Stimulation of the abdomen vagus nerve toward the medial end, almond nucleus, lateral and central nuclear somatostatin content decreased, the outer preoptic area hypothalamic ventrolateral medulla and paraventricular nucleus somatostatin content increased, antral gastric mucosa and muscle The levels of somatostatin also increased, suggesting that somatostatin in the amygdala and some nuclei of the hypothalamus may play a role in the central integrative activity of visceral afferent information.