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目的观察丙泊酚、氨胺酮、利多卡因(PKL)合剂用于肠镜检查的临床效果。方法70例需行肠镜检查的患者分为两组,P组丙泊酚用量为3 mg/kg;PKL组以丙泊酚用量计算,为0．6 mg/kg。比较两组的镇痛效果、丙泊酚的用量、对呼吸及循环的影响和苏醒时间的差异。结果PKL组镇痛效果强于P组,差异有统计学意义(P<0．05);PKL组的丙泊酚用量明显少于P组(P<0．05),且苏醒时间明显短于P组(P<0．05);PKL组的BP、HR与P组相比差异有统计学意义(P<0．05),诱导5 min内SpO2降低较P组明显(P<0．05)。结论PKL用于肠镜检查,镇静镇痛效果好,丙泊酚的用量明显减少,苏醒时间缩短,对循环有支持作用。
Objective To observe the clinical effect of propofol, amiketone and lidocaine (PKL) mixture for colonoscopy. Methods Seventy patients undergoing colonoscopy were divided into two groups: propofol in group P was 3 mg / kg and propofol in group PKL was 0.6 mg / kg. The analgesic effect, the amount of propofol, the effects on respiration and circulation, and the difference in recovery time were compared between the two groups. Results The analgesic effect of PKL group was stronger than that of P group (P <0.05). The dosage of propofol in PKL group was significantly less than that of P group (P <0.05), and the recovery time was significantly shorter than that of P group (P <0.05). There was significant difference between PKL group and P group (P <0.05). The decrease of SpO2 in PKL group was more significant than that in P group (P <0.05) ). Conclusion PKL for colonoscopy, sedative and analgesic effect is good, significantly reduced the amount of propofol, wake time shortening, has a supporting role in the cycle.