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目的应用液基薄层细胞学(TCT)检测宫颈病变,探讨宫颈病变新的相关因素及临床特点。方法采集756例受检者的宫颈脱落细胞,采用TCT技术,按TBS标准诊断,将细胞学检测结果进行分析。结果 756例患者中TCT阳性者53例,检出率为7.01%,不明确意义的非典型鳞状细胞42例占检查人数的(5.56%),CIN 10例占检查人数的1.32%,宫颈癌1例占检查人数的0.13%。从异常病例的构成比看,宫颈上皮细胞异常发生率31~40岁和41~50岁年龄组明显高于其他年龄组。结论新柏氏TCT作为妇科门诊常规检查,筛查宫颈癌及宫颈癌前病变具有重要价值。TCT检查结果与病理组织活检的符合率高。TCT作为无创性检测,能够及早发现宫颈早期病变,可成为筛查宫颈癌前病变的有效方法 ,预防及尽早发现宫颈癌的发生。
Objective To detect cervical lesions by liquid-based thin-layer cytology (TCT) and explore the new related factors and clinical features of cervical lesions. Methods The cervical exfoliated cells of 756 subjects were collected and diagnosed by TBS according to the TCT technique. The results of cytology were analyzed. Results The positive rate of TCT in 756 patients was 53 (7.01%). The number of atypical squamous cells with undefined significance was 42 (5.56%), 10 with CIN (1.32%) and cervical cancer 1 case accounted for 0.13% of the number of examinations. From the composition ratio of abnormal cases, the abnormal incidence of cervical epithelial cells 31 to 40 years old and 41 to 50 years old age group was significantly higher than the other age groups. Conclusion TCT as a new routine gynecological clinic screening, screening of cervical cancer and cervical precancerous lesions of great value. The coincidence rate between TCT examination and pathological biopsy was high. As a noninvasive detection, TCT can detect early cervical lesions and can be an effective screening method for precancerous lesions of cervical cancer, preventing and early detection of cervical cancer.