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本文主要讨论新型降压药─—血管紧张素Ⅱ（AngⅡ）受体桔抗剂在肾脏病中的应用。介绍AngⅡ受体的种类、分布、功能和常见AngⅡ受体桔抗剂的药代动力学特点；重新认识AngⅡ对肾脏的影响；比较AngⅡ受体持抗剂与血管紧张素转换酶抑制剂对肾脏的保护作用。
This article mainly discusses the application of a new antihypertensive drug - angiotensin II receptor antagonist in kidney disease. The type, distribution, function and the pharmacokinetic characteristics of angiotensin II receptor antagonist were introduced. The effects of angiotensin Ⅱ on kidney were reviewed. The effects of angiotensin II receptor antagonist and angiotensin converting enzyme inhibitor on kidney The protective effect.