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目的:探究硫酸镁与硝苯地平联合应用治疗妊高症的临床疗效,分析该方式的临床安全性。方法:选取我院2011年1月-2013年11月期间门诊收入的90例妊高症患者作为本组的研究对象,根据治疗方式的不同分为研究组与对照组,每组各45例。对照组给予硫酸镁治疗,研究组在对照组基础上给予硝苯地平治疗。观察经治疗后一般情况。结果:经治疗,研究组临床总有效率为97.8%,对照组为77.8%;两组在临床总有效率、血压与24h尿蛋白定量比较,差异有统计学意义(P<0.05)。结论:妊高症患者给予硝苯地平联合硫酸镁治疗,可保护心肌并改善缺氧症状,安全有效,值得推广。
Objective: To investigate the clinical efficacy of magnesium sulfate combined with nifedipine in the treatment of pregnancy induced hypertension, and to analyze the clinical safety of this method. Methods: Ninety cases of pregnancy-induced hypertension (PIH) in our hospital from January 2011 to November 2013 were selected as the study subjects and divided into study group and control group with 45 cases in each group according to different treatment methods. The control group was treated with magnesium sulfate, and the study group was given nifedipine on the basis of the control group. Observe the general situation after treatment. Results: After treatment, the total clinical effective rate was 97.8% in the study group and 77.8% in the control group. There was significant difference between the two groups in the clinical total effective rate and the blood pressure and the urinary protein excretion in 24 hours (P <0.05). Conclusion: Nifedipine and magnesium sulfate are given to patients with pregnancy-induced hypertension, which can protect the myocardium and improve the symptoms of hypoxia. It is safe and effective and should be promoted.