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目的探讨左炔诺孕酮宫内缓释系统(LNG-IUS)对子宫腺肌病的治疗效果。方法回顾性分析2006年9月至2009年2月间经LNG-IUS治疗的31例子宫腺肌病患者临床资料,对治疗前、治疗后3个月、12个月、3年患者的月经量、痛经VRS评分、子宫体积及不良反应进行比较。结果治疗后患者痛经症状明显减轻或消失,痛经评分、月经量明显减少,血红蛋白明显升高,与放置前比较差异有统计学意义(P<0.05);子宫体积较治疗前有所缩小,但差异无统计学意义(P>0.05)。部分患者出现较轻不良反应,自行缓解。结论 LNG-IUS治疗子宫腺肌病有效期较长,安全、方便、有效,近期疗效满意。
Objective To investigate the therapeutic effect of levonorgestrel intrauterine system (LNG-IUS) on adenomyosis. Methods The clinical data of 31 patients with adenomyosis treated by LNG-IUS from September 2006 to February 2009 were retrospectively analyzed. The menstrual flow rate of patients before treatment, 3 months, 12 months and 3 years after treatment , Dysmenorrhea VRS score, uterine volume and adverse reactions were compared. Results After treatment, the symptoms of dysmenorrhea were significantly reduced or disappeared. The scores of dysmenorrhea and menstruation were significantly decreased and hemoglobin was significantly increased (P <0.05). The volume of uterus contracted slightly before treatment, but the difference was significant No statistical significance (P> 0.05). Some patients with mild adverse reactions, self-remission. Conclusion LNG-IUS treatment of adenomyosis longer effective, safe, convenient and effective, the recent satisfactory results.