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目的:分析放射介入栓塞化疗在肝癌合并门静脉癌栓治疗中临床疗效。方法:选取2014年8月—2015年12月本院47例肝癌合并门静脉癌栓患者作为观察组,采用放射介入栓塞化疗疗法。同时,根据1:1比例选取本院同期47例肝癌合并门静脉癌栓患者作为对照组,采用肝动脉化疗药物灌注疗法,对2组患者临床治疗效果进行比较。结果:观察组肿瘤缩小程度>50%病例数量为13例(27.66%),对照组肿瘤缩小程度>50%病例数量为2例(4.26%),2组存在明显差异(P<0.05);观察组门静脉癌栓缩小率为46.67%,显著高于对照组(6.38%),2组具有明显差异(P<0.05)。结论:放射介入栓塞化疗方法治疗肝癌合并门静脉癌栓,临床效果明显,且能够缩小肿瘤体积及门静脉癌栓,值得广泛推广。
Objective: To analyze the clinical effect of radiotherapy and embolization chemotherapy in the treatment of hepatocellular carcinoma with portal vein tumor thrombus. Methods: Forty-seven hepatocellular carcinoma patients with portal vein tumor thrombus in our hospital from August 2014 to December 2015 were selected as the observation group and received radiotherapy and embolization chemotherapy. At the same time, according to the ratio of 1: 1, 47 patients with hepatocellular carcinoma with portal vein tumor thrombus in the same period of our hospital were selected as the control group. The therapeutic effect of hepatic artery chemotherapy was compared with that of the two groups. Results: In the observation group, the number of cases with tumor shrinkage> 50% was 13 cases (27.66%) in the observation group and 2 cases (4.26%) with the tumor reduction> 50% in the control group. There was significant difference between the two groups (P <0.05) The rate of thrombosis of portal vein cancer was 46.67%, which was significantly higher than that of control group (6.38%). There was significant difference between two groups (P <0.05). Conclusion: Radiographic interventional chemoembolization in the treatment of hepatocellular carcinoma with portal vein tumor thrombus has obvious clinical effect, and can reduce tumor volume and portal vein tumor thrombus, which is worth widely disseminating.