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目的:评价痰热清注射液治疗流行性腮腺炎合并脑膜脑炎的临床效果。方法:将我院2006年1月～2007年10月经脑电图和脑脊液确诊的84例流行性腮腺炎合并脑膜脑炎患儿随机分为痰热清注射液治疗组和对照组。治疗组42例,在退热、降低颅内压及肾上腺皮质激素对症及支持治疗的基础上加用痰热清注射液治疗,疗程3～7 d。对照组42例,在基础治疗上加用利巴韦林注射液,疗程3～7 d。结果:痰热清注射液能明显缩短患儿的热程和退热时间(P<0.05),头痛、呕吐、腮腺肿大的消失时间、脑膜刺激征消失时间痰热清注射液组明显短于对照组,差异均有统计学意义(P<0.05)。结论:痰热清注射液治疗流行性腮腺炎合并脑炎疗效肯定,抗病毒、退热、消肿作用确切,可作为治疗流行性腮腺炎合并脑膜脑炎的常规药物使用。
Objective: To evaluate the clinical effect of Tanreqing injection in the treatment of mumps combined meningoencephalitis. Methods: 84 cases of mumps meningoencephalitis diagnosed by EEG and cerebrospinal fluid in our hospital from January 2006 to October 2007 were randomly divided into Tanreqing injection group and control group. Treatment group 42 cases, in the fever, reduce intracranial pressure and adrenal cortex hormones symptomatic and supportive treatment based on the addition of Tanreqing injection, the treatment of 3 ~ 7 d. In the control group, 42 cases were treated with ribavirin injection on the basis of treatment for 3 to 7 days. Results: Tanreqing injection can significantly shorten the children’s heat stroke and antipyretic time (P <0.05), headache, vomiting, disappearance of parotid gland enlargement, disappearance of meningeal irritation time Tanreqing injection group was significantly shorter than Control group, the difference was statistically significant (P <0.05). Conclusion: Tanreqing injection is effective in treating mumps complicated with encephalitis, anti-virus, antipyretic, and swelling, and can be used as routine medicine for the treatment of mumps combined with meningoencephalitis.