应激和恐惧可产生镇痛作用,称为“应激镇痛”(stress-induced analgesia)。脑干的痛觉调制系统,尤其是延脑头端腹内侧区(RVM)的痛觉抑制神经元参与应激镇痛的发生。然而,近年来大量的研究表明,应激并不总是引起镇痛,相反,也可以引起 Stress and induced fear can produce analgesic effects, called stress-induced analgesia. The pain modulation system of the brain stem, especially the pain-suppressing neurons in the medial region of the medulla oblongata (RVM), is involved in the stress-induced analgesia. However, a large number of studies in recent years show that stress does not always cause analgesia, on the contrary, it can also cause