结核病是全世界由单一致病菌导致死亡最高的疾病,严重危害人类健康,因此保证抗结核类药物的质量具有重要意义。本文以常用抗结核药物为例,从国内外药典及文献报道两方面介绍了其含量测定方法,重点介绍高效液相色谱法,为建立快速、准确的高效液相色谱快速检验方法奠定基础。 Tuberculosis is the world’s leading cause of death caused by a single pathogen and seriously endangers human health. Therefore, ensuring the quality of anti-tuberculosis drugs is of great significance. In this paper, the commonly used anti-TB drugs, for example, from the domestic and foreign pharmacopoeia and literature coverage of two aspects of its content determination method, focusing on the introduction of high performance liquid chromatography, in order to establish a rapid and accurate method for rapid determination of high performance liquid chromatography laid the foundation.