骨髓除了作为造血组织恶性疾患的原发部位以外,又常常是实体瘤的转移部位。因骨髓受累可改变肿瘤患者的临床经过,并影响治疗反应及生存期,故在实体瘤患者常规地进行骨髓检查,对于正确的临床分期、骨髓贮备的估计、制定合理的治疗方案,以及判断予后等方面均有重要的临床意义。本文拟就一些文献中关于非造血及淋巴组织肿瘤所发生的骨髓侵犯加以介绍。 Reich在1935年首先观察到骨髓中的转移癌细胞。此后,有许多作者相继报告。近10 In addition to being the primary site of hematopoietic malignancies, bone marrow is often the site of metastases of solid tumors. Due to bone marrow involvement can change the clinical course of cancer patients, and affect the treatment response and survival, so routine bone marrow examination in patients with solid tumors, for the correct clinical stage, the estimation of bone marrow reserve, to develop a reasonable treatment plan, and to judge After the other aspects have important clinical significance. This article is about some of the literature on non-hematopoietic and lymphoid tissue tumor infringement introduced. Reich first observed in 1935 metastatic cancer cells in the bone marrow. Since then, many authors have reported. Nearly 10