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通过古今文献研究,掌握苦参炮制方法、药用部位及功能主治的发展与变迁。苦参古代炮制方法丰富,有苦酒煮、炙、米泔水浸制、炒制、酒制、醋制、油炒、焙等多种,现代则多以生品应用,其药用部位为去除根头和小支根的根部,但古代还有“去皮”或“去木取皮”的用法;古今文献对其功效的记载虽不尽相同,但基本可以归纳为清热燥湿、杀虫、利尿,但在临床应用方面仍有不同之处。苦参的古今文献研究提示,应加强对古代文献的挖掘,开展基于古代炮制方法的物质基础与其功效的相关性研究,为揭示苦参炮制原理、研发基于不同炮制方法的苦参或苦参复方创新药物提供新思路。
Through ancient and modern literature research, grasp the processing methods of Sophora, medicinal parts and functional indications of the development and changes. Ophiopogon japonicus ancient processing methods are rich, with bitter wine, Sunburn, rice water immersion system, frying, wine, vinegar system, oil fried, baking and other modern times, more than the application of raw materials, the medicinal parts of the removal Roots and roots of small roots, but in ancient times there are “peeled ” or “to wood to take the skin ” usage; ancient and modern literature on the efficacy of the record is not the same, but the basic can be summed up as dry heat Wet, insecticidal, diuretic, but there are still differences in clinical application. The research on ancient and modern literature of Sophora flavescensum suggests that the excavation of ancient documents should be strengthened and the correlation between the material basis and its efficacy based on the ancient method of processing should be studied. To reveal the principle of the processing of Sophora flavescens, Innovative drugs provide new ideas.