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目的从手术切除的33例肺结核标本的细菌学结果评价外科治疗肺结核的意义。方法采集33例自2008年10月—2009年6月在北京胸科医院行肺结核手术的手术切除标本,将标本进行结核分枝杆菌罗氏培养及菌种鉴定和药物敏感试验,与术前痰菌结果进行比较。结果手术标本中结核分枝杆菌培阳率为72.7%(24/33),痰中结核分枝杆菌的培阳率为21.2%(7/33)。24例培养阳性的菌株进行药物敏感试验,显示均有不同程度的耐药性。对于影像学上显示已经稳定的纤维化、钙化病灶,结核分枝杆菌培养阳性率仍较高。结论手术治疗肺结核是避免复发和产生耐药结核病的有效手段之一。
Objective To evaluate the significance of surgical treatment of pulmonary tuberculosis from the bacteriological results of 33 cases of pulmonary tuberculosis resected surgically. Methods Thirty-three cases of surgical resection of pulmonary tuberculosis in Beijing Chest Hospital from October 2008 to June 2009 were collected. The specimens were subjected to Mycobacterium tuberculosis Roche culture and strain identification and drug sensitivity test, The results are compared. Results The culture rate of Mycobacterium tuberculosis in surgical specimens was 72.7% (24/33), and the positive rate of Mycobacterium tuberculosis in sputum was 21.2% (7/33). 24 cases of positive strains tested for drug sensitivity tests showed that there are varying degrees of resistance. For the imaging studies have shown stable fibrosis, calcification lesions, the positive rate of M. tuberculosis culture is still high. Conclusion Surgical treatment of pulmonary tuberculosis is one of the effective ways to avoid recurrence and develop drug-resistant tuberculosis.