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目的:讨进展性脑卒中采用阿司匹林联合氯吡格雷治疗的临床效果和安全性。方法:取我院2013年12月-2015年2月收治的50例进展性脑卒中患者,随机分为对照组和观察组,各25例。对照组仅采用阿司匹林治疗,观察组在此基础上联合氯吡格雷进行治疗,观察并比较两组患者的临床治疗效果和不良反应。结果:照组总有效率72.0%,观察组总有效率92.0%,两组总有效率相比差异显著,具有统计学意义(P<0.05)。两组患者用药治疗期间及治疗后,均未发生不良反应,并无患者肝肾功能受到影响的症状发生。结论:展性脑卒中采用阿司匹林联合氯吡格雷治疗的临床效果显著,并且安全性比较高,值得我们在临床上大力推广。
Objective: To investigate the clinical effect and safety of aspirin plus clopidogrel in patients with advanced stroke. Methods: Fifty patients with progressive stroke admitted from December 2013 to February 2015 in our hospital were randomly divided into control group and observation group, with 25 cases in each group. The control group was treated with aspirin alone. The observation group was treated with clopidogrel on the basis of this observation. The clinical effects and adverse reactions of the two groups were observed and compared. Results: The total effective rate was 72.0% in the observation group and 92.0% in the observation group. There was significant difference between the two groups in total effective rate (P <0.05). No adverse reactions occurred in both groups during and after treatment, and no symptoms of liver and kidney function were affected. Conclusion: The clinical effect of aspirin combined with clopidogrel in patients with malaise is significant and the safety is relatively high. It is worth our clinical promotion.