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鼻咽癌(NPC)病人的咀嚼肌一旦失神经支配(DMM)就会在MRI上呈T2延长(高信号),静脉造影后明显增强,还可有肌肉萎缩和脂肪性变。DMM的出现,强烈提示下颌神经(Ⅴ3)有NPC浸润,故应努力搜寻。除非在Ⅴ3径路上包括卵圆孔,三叉神经池(即Meckel氏小腔),或海绵窦无新的、日渐增大的NPC累及灶,才可对放疗过的病人考虑为Ⅴ3放射损伤所致。NPC如果向侧方扩展侵入DMM,则该被侵的DMM的MRI信号即转变成为NPC的信号。
Nasopharyngeal carcinoma (NPC) patients, once denervated (DMM), exhibit prolonged T2 (high signal) on MRI and significantly increase after venography, as well as muscle atrophy and steatosis. The emergence of DMM, strongly suggest that the mandibular nerve (Ⅴ 3) with NPC invasion, it should be hard to search. Radiation-treated patients may be considered radiation injury Ⅴ, unless there are foramen ovales, trigeminal pools (ie, Meckel’s cavities) in path V3, or no new, enlarged NPC-associated lesions in cavernous sinus . If the NPC expands sideways into the DMM, then the invading DMM’s MRI signal is transformed into a NPC signal.