目的探讨达英-35、二甲双胍和克罗米芬三种药物治疗多囊卵巢综合征伴不孕的临床疗效。方法选取多囊卵巢综合征伴不孕的患者90例,随机分成三组,每组30例,分别应用达英-35、二甲双胍和克罗米芬物治疗,比较各组患者治愈率。结果二甲双胍组的排卵率为23.3%,妊娠率为6.7%;达英-35组的排卵率为43.3%,妊娠率为13.3%;克罗米芬组的排卵率为60%,妊娠率为33.3%。结论克罗米芬能最大程度上促进患者排卵,提高患者妊娠率,达英-35疗效次之,而二甲双胍的疗效最差。 Objective To investigate the clinical efficacy of three drugs Ying -35, metformin and clomiphene in the treatment of polycystic ovary syndrome with infertility. Methods Ninety patients with polycystic ovary syndrome and infertility were randomly divided into three groups (30 in each group). The patients were treated with Ying-35, metformin and clomiphene citrate respectively. The cure rate of each group was compared. Results The metformin group had an ovulation rate of 23.3% and a pregnancy rate of 6.7%. The ovulation rate was 43.3% in the Yingying-35 group and the pregnancy rate was 13.3%. The rate of ovulation in the clomiphene group was 60% and the pregnancy rate was 33.3%. Conclusions Clomiphene can promote ovulation to the greatest extent and improve the pregnancy rate of patients. The response rate of Ying-35 is the second, and the efficacy of metformin is the worst.