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目的:探讨重症肌无力危象发生的危险因素。方法:选择在笔者所在医院接受治疗的130例重症肌无力患者作为研究对象,对患者的临床资料进行回顾分析,并采进行电话回访。结果:全部130例患者中,共计出现21例重症肌无力危象,占16.2%。重症肌无力危象与感染、抗胆碱酯酶药物间断、过度劳累、情感创伤、糖皮质激素使用、胸腺切除术、高温等因素有关。结论:合并感染、抗胆碱酯酶药物间断、过度劳累、情感创伤、糖皮质激素使用、胸腺切除术、高温等因素是造成重症肌无力危象的主要因素,充分认识这些危险因素有利于降低危象的发生率。
Objective: To explore the risk factors of myasthenia gravis crisis. Methods: One hundred and thirty cases of myasthenia gravis treated in the author’s hospital were selected as the research object. The clinical data of the patients were retrospectively analyzed and telephone interviews were conducted. Results: Totally 21 patients with myasthenia gravis crisis accounted for 16.2% of all 130 patients. Myasthenia gravis crisis and infection, anticholinesterase drug discontinuity, over exertion, emotional trauma, glucocorticoid use, thymectomy, high temperature and other factors. Conclusions: The main risk factors for myasthenia gravis crisis are co-infection, anticholinesterase discontinuation, over-exertion, emotional trauma, glucocorticoid use, thymectomy and hyperthermia. A full understanding of these risk factors is beneficial to reduce The incidence of crisis.