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目的探讨肝硬化患者植物神经功能和低氧血症变化的关系。方法以综合指标测定法测定30例肝硬化患者的植物神经功能并抽动脉血检测动脉血氧分压。结果按ChildPugh分级,在植物神经功能测定中,B级13例,正异常值0例,正常值8例,负异常值5例,异常率为38.46%;C级17例,正异常值1例,正常值6例,负异常值10例,异常率为64.71%。说明植物神经功能损害与肝脏损害呈正相关。在动脉血氧分压测定中,B级轻度低氧血症6例,中度低氧血症5例,重度低氧血症2例;C级轻度低氧血症0例,中度低氧血症5例,重度低氧血症12例。B级和C级两组间比较差异有显著性(P<0.005)。结论多数肝硬化患者植物神经功能和低氧血症异常与肝脏功能损害呈相关性。
Objective To investigate the relationship between autonomic function and hypoxemia in cirrhotic patients. Methods The autonomic nerve function was measured in 30 patients with cirrhosis by the comprehensive index method and the blood pressure was measured by pulsed blood. The results were graded according to ChildPugh. In the autonomic nerve function test, 13 cases were in grade B, 0 cases were positive, 8 cases were normal and 5 cases were negative. The abnormal rate was 38.46% , Normal 6 cases, negative abnormal 10 cases, the abnormal rate was 64.71%. Shows that autonomic dysfunction and liver damage was positively correlated. In the determination of arterial oxygen partial pressure, B grade mild hypoxemia in 6 cases, moderate hypoxemia in 5 cases, severe hypoxemia in 2 cases; C mild hypoxemia in 0 cases, moderate 5 cases of hypoxemia, 12 cases of severe hypoxemia. There was significant difference between B and C groups (P <0.005). Conclusions Abnormalities of autonomic function and hypoxemia in most patients with liver cirrhosis are correlated with liver dysfunction.