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纳米银是指粒径在纳米级(1～100nm)的金属银单质。由于具有特殊的性能,纳米银在多个领域广泛应用。在医学领域中,纳米银作为抗菌剂的主要成分大量应用于临床治疗。因此,纳米银的潜在毒性及其对健康的影响引起了人们的广泛关注,研究表明纳米银存在不同程度的细胞毒性。该文综述了纳米银的医学生物学特性及其潜在毒性,认为透彻认识纳米银的潜在毒性及其机理才能保证纳米银在临床治疗中的安全应用。
Nano silver refers to the particle size in the nanoscale (1 ~ 100nm) metallic silver element. Due to its special properties, nano-silver is widely used in many fields. In the field of medicine, nano-silver is widely used as an antibacterial agent in clinical treatment. Therefore, the potential toxicity of nanosilver and its health effects have aroused widespread concern. Studies have shown that nanosilver has some degree of cytotoxicity. In this paper, the biological characteristics and potential toxicity of nanosilver are summarized. It is considered that the potential toxicity and mechanism of nanosilver can be fully understood to ensure the safe application of nanosilver in clinical treatment.