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目的探讨解脲脲原体(Ureaplasma Urealyticum UU)对不育男性精子形态的影响。方法对360例男性不育患者的精液进行(UU)培养,同时用改良巴氏法对精子进行形态学分析。解脲脲原体(UU)阳性(感染)者,给予抗生素治疗,停药后7天再行解脲脲原体(UU)培养,同时做精子形态学分析。结果360例男性不育患者中,解脲脲原体阳性的有162例,占总数的45%。阴性的患者平均精子畸形率约31.5%,阳性患者的平均约56.5%,存在着显著差异(P<0.05)。经治疗后转阴的患者的精子畸形率平均约33.5%,较治疗前有显著差异(P<0.05)。结论解脲脲原体(UU)感染明显增加不育男性精子的畸形率,从而影响男性的生育力,对其进行及时治疗是必须和有效的。
Objective To investigate the effect of Ureaplasma Urealyticum UU on sperm morphology in infertile men. Methods The semen of 360 male infertility patients were cultured (UU), and the sperm morphology was analyzed by modified Papanicolaou method. Ureaplasma urealyticum (UU) positive (infected) who were given antibiotics, 7 days after drug withdrawal Ureaplasma urealyticum (UU) culture, at the same time do sperm morphological analysis. Results Of the 360 male infertility patients, 162 were positive for U. urealyticum, accounting for 45% of the total. Negative patients had a mean sperm deformity rate of about 31.5% and an average of 56.5% of positive patients, there was a significant difference (P <0.05). The sperm deformity rate of the negative patients after treatment was about 33.5% on average, which was significantly different from that before treatment (P <0.05). Conclusion UU infection significantly increases the abnormality rate of sperm in infertile men, which affects male fertility. It is necessary and effective to treat UU infection promptly.